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Background: Heat effects on respiratory mortality are known, mostly from time-series studies of city-wide data. A limited number of studies have been conducted at the national level or covering non-urban areas. Effect modification by area-level factors has not been extensively investigated. Our study assessed the heat effects on respiratory mortality at a small administrative area level in Norway, Germany, and England and Wales, in the warm period (May-September) within 1996-2018. Also, we examined possible effect modification by several area-level characteristics in the framework of the EU-Horizon2020 EXHAUSTION project.

Background: Short-term associations between heat and cardiovascular disease (CVD) mortality have been examined mostly in large cities. However, different vulnerability and exposure levels may contribute to spatial heterogeneity. This study assessed heat effects on CVD mortality and potential vulnerability factors using data from three European countries, including urban and rural settings.

As the climate warms, increasing heat-related health risks are expected, and can be exacerbated by the urban heat island (UHI) effect. UHIs can also offer protection against cold weather, but a clear quantification of their impacts on human health across diverse cities and seasons is still being explored. Here we provide a 500 m resolution assessment of mortality risks associated with UHIs for 85 European cities in 2015-2017. The findings urge strategies aimed at designing healthier cities to consider the seasonality of UHI impacts and to account for social costs, their controlling factors, and intra-urban variability.

The effects of short-term exposure to increased temperature on mortality are known, mostly based on time-series studies of city-wide data, whereas the evidence on temperature- air pollution interaction is limited. We investigated the association of short-term exposure to high temperatures with mortality in the Attica prefecture, Greece, by municipality, in the warm period (May-September) during 2000-2016, assessing daily air pollution exposure as effect modifier.