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Evidences on adaptive mechanisms for cardiorespiratory diseases regarding extreme temperatures and air pollution: A comparative systematic review

Helena Madureira, Maria Pacheco, Carlos Sousa, Ana Monteiro, Francesca De’-Donato, Manuela De-Sario

The objective of this paper is to explore the evidence of adaptive mechanisms for cardiorespiratory diseases regarding extreme temperatures and air pollution by comparing the results of two systematic literature review (SLR) processes sharing the same initial research question but led by two research groups with different academic backgrounds working in the same multidisciplinary team.

https://www.sciencedirect.com/science/article/pii/S2666683921000353Evidences on adaptive mechanisms for cardiorespiratory diseases regarding extreme temperatures and air pollution: A comparative systematic review

Geography and Sustainability
12 September 2021
Publication

Combined impacts of climate and air pollution on human health and agricultural productivity

Jana Sillmann, Kristin Aunan, Lisa Emberson, Patrick Bûker, Bob Van Oort, Connie O’Neill, Noelia Otero, Divya Pandey, Anouk Brisebois

Climate change and air pollution can interact to amplify risks to human health and crop production. Closer integration of climate change and air pollution both in terms of impact assessment for human health and agricultural productivity and respective policy development is needed.

Combined impacts of climate and air pollution
3.9.2021
Publication

Mortality risk attributable to wildfire-related PM2·5 pollution: a global time series study in 749 locations

Gongbo Chen, Yuming Guo, Xu Yue, Shilu Tong, Antonio Gasparrini, Michelle L Bell, Ben Armstrong, Joel Schwartz, Jouni J K Jaakkola, Antonella Zanobetti, Eric Lavigne, Paulo Hilario Nascimento Saldiva, Haidong Kan, Dominic Royé, Ai Milojevic, Ala Overcenco, Aleš Urban, Alexandra Schneider, Alireza Entezari, Ana Maria Vicedo-Cabrera, Ariana Zeka, Aurelio Tobias, Baltazar Nunes, Barrak Alahmad, Bertil Forsberg, Shih-Chun Pan, Carmen Íñiguez, Caroline Ameling, César De la Cruz Valencia, Christofer Åström, Danny Houthuijs, Do Van Dung, Evangelia Samoli, Fatemeh Mayvaneh, Francesco Sera, Gabriel Carrasco-Escobar, Yadong Lei, Hans Orru, Ho Kim, Iulian-Horia Holobaca, Jan Kyselý, João Paulo Teixeira, Joana Madureira, Klea Katsouyanni, Magali Hurtado-Díaz, Marek Maasikmets, Martina S Ragettli, Masahiro Hashizume, Massimo Stafoggia, Mathilde Pascal, Matteo Scortichini, Micheline de Sousa Zanotti Stagliorio Coêlho, Nicolás Valdés Ortega, Niilo R I Ryti, Noah Scovronick, Patricia Matus, Patrick Goodman, Rebecca M Garland, Rosana Abrutzky, Samuel Osorio Garcia, Shilpa Rao, Simona Fratianni, Tran Ngoc Dang, Valentina Colistro, Veronika Huber, Whanhee Lee, Xerxes Seposo, Yasushi Honda, Yue Leon Guo, Tingting Ye, Wenhua Yu, Michael J Abramson, Jonathan M Samet, Shanshan Li

Many regions of the world are now facing more frequent and unprecedentedly large wildfires. However, the association between wildfire-related PM2·5 and mortality has not been well characterised. We aimed to comprehensively assess the association between short-term exposure to wildfire-related PM2·5 and mortality across various regions of the world.

Short-term exposure to wildfire-related PM2·5 was associated with increased risk of mortality. Urgent action is needed to reduce health risks from the increasing wildfires.

Mortality risk attributable to wildfire-related PM2·5 pollution: a global time series study in 749 locations

The Lancet Planetary Health
1 September 2021
Publication

Seasonal variation in mortality and the role of temperature: a multi-country multi-city study

Lina Madaniyazi, Ben Armstrong, Yeonseung Chung, Chris Fook Sheng Ng, Xerxes Seposo, Yoonhee Kim, Aurelio Tobias, Yuming Guo, Francesco Sera, Yasushi Honda,  Antonio Gasparrini, Masahiro Hashizume,

This study suggests that seasonality of mortality is importantly driven by temperature, most evidently in temperate/continental climate zones, and that warmer locations show stronger seasonal variations in mortality, which is related to a stronger effect of temperature.

Seasonal variation in mortality and the role of temperature: a multi-country multi-city study

International Journal of Epidemiology
1 September 2021
Publication

Global, regional, and national burden of mortality associated with non-optimal ambient temperatures from 2000 to 2019: a three-stage modelling study

Qi Zhao, Yuming Guo, Tingting Ye, Antonio Gasparrini, Shilu Tong, Ala Overcenco, Aleš Urban, Alexandra Schneider, Alireza Entezari, Ana Maria Vicedo-Cabrera, Antonella Zanobetti, Antonis Analitis, Ariana Zeka, Aurelio Tobias, Baltazar Nunes, Barrak Alahmad, Ben Armstrong, Bertil Forsberg, Shih-Chun Pan, Carmen Íñiguez, Caroline Ameling, César De la Cruz Valencia, Christofer Åström, Danny Houthuijs, Do Van Dung, Dominic Royé, Ene Indermitte, Eric Lavigne, Fatemeh Mayvaneh, Fiorella Acquaotta, Francesca de'Donato, Francesco Di Ruscio, Francesco Sera, Gabriel Carrasco-Escobar, Haidong Kan, Hans Orru, Ho Kim, Iulian-Horia Holobaca, Jan Kyselý, Joana Madureira, Joel Schwartz, Jouni J K Jaakkola, Klea Katsouyanni, Magali Hurtado Diaz, Martina S Ragettli, Masahiro Hashizume, Mathilde Pascal, Micheline de Sousa Zanotti Stagliorio Coélho, Nicolás Valdés Ortega, Niilo Ryti, Noah Scovronick, Paola Michelozzi, Patricia Matus Correa, Patrick Goodman, Paulo Hilario Nascimento Saldiva, Rosana Abrutzky, Samuel Osorio, Shilpa Rao, Simona Fratianni, Tran Ngoc Dang, Valentina Colistro, Veronika Huber, Whanhee Lee, Xerxes Seposo, Yasushi Honda, Yue Leon Guo, Michelle L Bell, Shanshan Li

Non-optimal temperatures are associated with a substantial mortality burden, which varies spatiotemporally. Our findings will benefit international, national, and local communities in developing preparedness and prevention strategies to reduce weather-related impacts immediately and under climate change scenarios.

Global, regional, and national burden of mortality associated with non-optimal ambient temperatures from 2000 to 2019: a three-stage modelling study
The Lancet Planetary Health
1 July 2021
Publication

The burden of heat-related mortality attributable to recent human-induced climate change

A. M. Vicedo-Cabrera, N. Scovronick, F. Sera, D. Royé, R. Schneider, A. Tobias, C. Astrom, Y. Guo, Y. Honda, D. M. Hondula, R. Abrutzky, S. Tong, M. de Sousa Zanotti Stagliorio Coelho, P. H. Nascimento Saldiva, E. Lavigne, P. Matus Correa, N. Valdes Ortega, H. Kan, S. Osorio, J. Kyselý, A. Urban, H. Orru, E. Indermitte, J. J. K. Jaakkola, N. Ryti, M. Pascal, A. Schneider, K. Katsouyanni, E. Samoli, F. Mayvaneh, A. Entezari, P. Goodman, A. Zeka, P. Michelozzi, F. de’Donato, M. Hashizume, B. Alahmad, M. Hurtado Diaz, C. De La Cruz Valencia, A. Overcenco, D. Houthuijs, C. Ameling, S. Rao, F. Di Ruscio, G. Carrasco-Escobar, X. Seposo, S. Silva, J. Madureira, I. H. Holobaca, S. Fratianni, F. Acquaotta, H. Kim, W. Lee, C. Iniguez, B. Forsberg, M. S. Ragettli, Y. L. L. Guo, B. Y. Chen, S. Li, B. Armstrong, A. Aleman, A. Zanobetti, J. Schwartz, T. N. Dang, D. V. Dung, N. Gillett, A. Haines, M. Mengel, V. Huber & A. Gasparrini

Climate change affects human health; however, there have been no large-scale, systematic efforts to quantify the heat-related human health impacts that have already occurred due to climate change. Here, we use empirical data from 732 locations in 43 countries to estimate the mortality burdens associated with the additional heat exposure that has resulted from recent human-induced warming, during the period 1991–2018. Across all study countries, we find that 37.0% (range 20.5–76.3%) of warm-season heat-related deaths can be attributed to anthropogenic climate change and that increased mortality is evident on every continent. Burdens varied geographically but were of the order of dozens to hundreds of deaths per year in many locations. Our findings support the urgent need for more ambitious mitigation and adaptation strategies to minimize the public health impacts of climate change.

The burden of heat-related mortality attributable to recent human-induced climate change

Nature Climate Change
31 May 2021
Publication

Heat Stress Indicators in CMIP6: Estimating Future Trends and Exceedances of Impact‐Relevant Thresholds

Clemens Schwingshackl, Jana Sillmann, Ana Maria Vicedo‐Cabrera, Marit Sandstad, Kristin Aunan

Global warming is leading to increased heat stress in many regions around the world. An extensive number of heat stress indicators (HSIs) has been developed to measure the associated impacts on human health.

Heat Stress Indicators in CMIP6

AGU.org, Earth's Future
13.02.2021
Publication

Air pollution declines during COVID-19 lockdowns mitigate the global health burden

Zander S.Venter, Kristin Aunan, Sourangsu Chowdhury, Jos Lelieveld

The lockdown response to COVID-19 has resulted in an unprecedented reduction in global economic activity and associated air pollutant levels, especially from a decline in land transportation.

Air pollution declines during COVID-19 lockdowns mitigate the global health burden

Elsevier, Environmental Research
January 2021
Publication

Evaluation of CMIP5 and CMIP6 simulations of historical surface air temperature extremes using proper evaluation methods

Thordis L Thorarinsdottir, Jana Sillmann, Marion Haugen, Nadine Gissibl and Marit Sandstad

Reliable projections of extremes by climate models are becoming increasingly important in the context of climate change and associated societal impacts.

Find the full publication here.

Environmental Research Letters, Volume 15, Number 12
11.12.2020
Publication

Projections of excess mortality related to diurnal temperature range under climate change scenarios: a multi-country modelling study

Lee W, Kim Y, Sera F, Gasparrini A, Park R, Michelle Choi H, Prifti K, Bell ML, Abrutzky R, Guo Y, Tong S, de Sousa Zanotti Stagliorio Coelho M, Nascimento Saldiva PH, Lavigne E, Orru H, Indermitte E, Jaakkola JJK, Ryti NRI, Pascal M, Goodman P, Zeka A, Hashizume M, Honda Y, Hurtado Diaz M, César Cruz J, Overcenco A, Nunes B, Madureira J, Scovronick N, Acquaotta F, Tobias A, Vicedo-Cabrera AM, Ragettli MS, Guo YL, Chen BY, Li S, Armstrong B, Zanobetti A, Schwartz J, Kim H.

Various retrospective studies have reported on the increase of mortality risk due to higher diurnal temperature range (DTR). This study projects the effect of DTR on future mortality across 445 communities in 20 countries and regions.

Projections of excess mortality

The Lancet Planetary Health
November 2020
Publication

A Satellite-Based Spatio-Temporal Machine Learning Model to Reconstruct Daily PM2.5 Concentrations across Great Britain

Rochelle Schneider, Ana M. Vicedo-Cabrera, Francesco Sera, Pierre Masselot, Massimo Stafoggia, Kees de Hoogh, Itai Kloog, Stefan Reis, Massimo Vieno, and Antonio Gasparrini

Data from satellites, reanalysis, and chemical transport models offer additional information used to reconstruct pollution concentrations at high spatio-temporal resolutions.

A Satellite-Based Spatio-Temporal Machine Learning Model

Remote sensing
20.11.2020
Publication

Cardiovascular risks of climate change

Annette Peters & Alexandra Schneider

Extreme heat events are now more frequent in many parts of the world as a result of climate change. The combined effects of heat, air pollution, individual age, and socioeconomic and health status need to be considered in order to prevent and treat cardiovascular diseases effectively.

Cardiovascular risks of climate change

Nature Reviews Cardiology volume 18, pages1–2(2021)
09.11.2020
Publication

Air Conditioning and Heat-related Mortality

Sera F, Hashizume M, Honda Y, Lavigne E, Schwartz J, Zanobetti A, Tobias A, Iniguez, Vicedo-Cabrera AM, Blangiardo M, Armstrong B, Gasparrini A

Air conditioning has been proposed as one of the key factors explaining reductions of heat-related mortality risks observed in the last decades. However, direct evidence is still limited.

Air Conditioning and Heat-related Mortality

Epidemiology: November 2020 - Volume 31 - Issue 6 - p 779-787
November 2020
Publication

Excess mortality during the COVID-19 outbreak in Italy: a two-stage interrupted time-series analysis

Matteo Scortichini, Rochelle Schneider dos Santos, Francesca De’ Donato, Manuela De Sario, Paola Michelozzi, Marina Davoli, Pierre Masselot, Francesco Sera, Antonio Gasparrini

Italy was the first country outside China to experience the impact of the COVID-19 pandemic, which resulted in a significant health burden. This study presents an analysis of the excess mortality across the 107 Italian provinces, stratified by sex, age group and period of the outbreak.

Excess mortality during the COVID-19 outbreak in Italy

International Journal of Epidemiology, Volume 49, Issue 6
14.10.2020
Publication

Nonlinear temperature-suicide association in Japan from 1972 to 2015: Its heterogeneity and the role of climate, demographic, and socioeconomic factors

Kisung Sim, Yoonhee Kim, Masahiro Hashizume, Antonio Gasparrini, Ben Armstrong, Francesco Sera, Chris Fook Sheng Ng, Yasushi Honda, Yeonseung Chung

It has been reported that suicide is associated with ambient temperature; however, the heterogeneity in this association and its underlying factors have not been extensively investigated.

Nonlinear temperature-suicide association in Japan from 1972 to 2015.

ScienceDirect, Environment International, Volume 142
September 2020
Publication

Temperature-related excess mortality in German cities at 2 °C and higher degrees of global warming

Veronika Huber, Linda Krummenauer, Cristina Peña-Ortiz, Stefan Lange, Antonio Gasparrini, Ana M. Vicedo-Cabrera, Ricardo Garcia-Herrera, Katja Frieler

Investigating future changes in temperature-related mortality as a function of global mean temperature (GMT) rise allows for the evaluation of policy-relevant climate change targets. So far, only few studies have taken this approach, and, in particular, no such assessments exist for Germany, the most populated country of Europe.

Temperature-related excess mortality in German cities

ScienceDirect, Environmental Research, Volume 186
July 2020
Publication

Association of Social Distancing, Population Density, and Temperature With the Instantaneous Reproduction Number of SARS-CoV-2 in Counties Across the United States

David Rubin, Jing Huang, Brian T. Fisher, Antonio Gasparrini, Vicky Tam, Lihai Song, Xi Wang, Jason Kaufman, Kate Fitzpatrick, Arushi Jain, Heather Griffis, Koby Crammer, Jeffrey Morris, Gregory Tasian.

In this cohort study of 211 counties in 46 states, social distancing, temperate weather, and lower population density were associated with a decrease in the instantaneous reproduction number of SARS-CoV-2.

Association of Social Distancing, Population Density, and Temperature

Jama Network Open
23.07.2020
Publication

COVID-19 lockdowns cause global air pollution declines

Zander S. Venter, Kristin Aunan, Sourangsu Chowdhury, Jos Lelieveld

We find that, after accounting for meteorological variations, lockdown events have reduced the population-weighted concentration of nitrogen dioxide and particulate matter levels by about 60% and 31% in 34 countries, with mixed effects on ozone. Reductions in transportation sector emissions are largely responsible for the NO2 anomalies.

COVID-19 lockdowns cause global air pollution declines

PNAS
28.07.2020
Publication

Deaths Attributable to Air Pollution in Nordic Countries: Disparities in the Estimates

Heli Lehtomäki,Camilla Geels, Jørgen Brandt, Shilpa Rao, Katarina Yaramenka, Stefan Åström, Mikael Skou Andersen, Lise M. Frohn, Ulas Im, Otto Hänninen

Particulate matter air pollution is widely considered as the leading environmental cause of premature mortality. However, there are substantial differences in the estimated health burden between the assessments.

Deaths Attributable to Air Pollution in Nordic Countries

Atmosphere, Volume 11, Issue 5
05.05.2020